A truly all natural alternative to sugar is finally here! Since the 16th century, Guarani Indians of Paraguay have used the herb Stevia to sweeten. Even though it’s extracts can be 300 times sweeter than sugar, as of 1999, steviol glycosides had not approved for use as a sweetener in the European Union. Despite it being banned as a food additive, I have been using stevia extract for years, as it can be purchased as a dietary supplement. For my type 1 diabetic spouse, it is a great replacement for sugar. This natural sweetener wasn’t allowed in foods, toothpastes, and such due to insufficient available data. In fact, some studies stated that steviol, a metabolite of stevioside, is a mutagenic and may also cause reproductive toxicity. Almost 10 years later, the Joint Expert Committee on Food Additives (JEFCA) of the United Nations’ Food and Agriculture Organization and the World Health Organization (WHO) reviewed steviol glycosides again. This time they found positive results, thus setting a temporary ADI (acceptable daily intake) level for steviol glycosides.
In 1999, the European Commission ’s Scientific Commitee on Food released their “Opinion on Stevioside as a Sweetener”. In it, they cite a study where steviol shows mutagenic activity, in vitro, meaning in a test tube. Without evidence that steviol is not mutagenic in vivo, meaning in the body, the EU obviosly could not approve it’s used in foods. However, the JEFCA/WHO report states new data has been reviewed and in actuality, steviol is toxic in vitro but studies, in vivo, on rats, mice, & hamsters show that steviol is not toxic, even at doeses of 8000mg per kg of bodyweight! I agree that although steviol may be toxic in the right test tube environment, does not mean that it acts the same way in the body.
Another reason the EU wasn’t ready to approve steviol glycosides in 1999 was the conflicting information about steviol’s affects on the reproductive system. One study shows that stevia extracts given to rats in thier drinking water causes infertility for up to 2 months. Another shows decreased seminal vesicle weight. The European Commission ’s Scientific Commitee on Food even notices, “However, in most old studies of reproduction performance the administered dose has been low and not comparable to those used in other toxicological studies. Furthermore, the adminstered stevioside extracts have chemically not been adequately described.” The way the extract is prepared affects the results of the study. Three more studies are cited that show stevioside is not developmentally toxic in hamsters or rats but steviol can be at very high doses. JEFCA/WHO says “The adverse reproductive effects associated with administration of (stevia)…were unlikely to be caused by steviol glycosides.” I agree, people around the world have been using stevia, and it’s extracts, without negative reproductive effects for generations. We are daily stevia users in our home and we had no infertility issues.
I know here in the US, forms of stevia have been approved and are becoming available to the consumer. As for the EU, an application has been submitted to permit steviol glycosides, as a food additive, and it is being evaluated. According to Gloria Obasogie at the Food Standards Agency, “The assessment process can be lenghty and if a positive opinion is gien, it may take a couple of years for steviol glycosides to be permitted in law.” For now, consumers can still get it like we have been, as a dietary supplement.